Diazolidinyl urea
Diazolidinyl urea
CAS: 78491-02-8
Molecular Formula: C8H14N4O7
Diazolidinyl urea - Names and Identifiers
| Name | Diazolidinyl urea |
| Synonyms | GerMall IS-45 roxymethyl)urea Diazolidinylurea Diazolidinyl urea Diazolidinyl urea (DU) 1-imidazolidin-1-ylurea Germall-2 Powder Antiseptic Diazolidiny1 Urea(GerMall Ⅱ ) Diazolidinyl Urea (diazonium imidazolidinyl urea) 1-[1,3-bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-1,3-bis(hydroxymethyl)urea N-[1,3-Bis(hydroxymethyl)-2,5-dioxoimidazolidin-4-yl]-N,N'-bis(hydroxymethyl)urea N-(1,3-Bis(hydroxymethyl)-2,5-dioxo-4-imidazolidinyl)-N,N'-bis(hydroxymethyl)-urea N-(Hydroxymethyl)-N-(1,3-dihydroxymethyl-2,5-dioxo-4-imidazolidinyl)-N'-(hydroxymethyl)urea |
| CAS | 78491-02-8 |
| EINECS | 278-928-2 |
| InChI | InChI=1/C4H10N4O/c5-4(9)7-8-2-1-6-3-8/h6H,1-3H2,(H3,5,7,9) |
| InChIKey | SOROIESOUPGGFO-UHFFFAOYSA-N |
Diazolidinyl urea - Physico-chemical Properties
| Molecular Formula | C8H14N4O7 |
| Molar Mass | 278.22 |
| Density | 1.4734 (rough estimate) |
| Boling Point | 421.04°C (rough estimate) |
| Water Solubility | 1000g/L at 20℃ |
| Solubility | Water (Slightly) |
| Vapor Presure | 0Pa at 20℃ |
| Appearance | Solid |
| Color | White to Off-White |
| Merck | 14,3000 |
| pKa | 11.22±0.46(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| Refractive Index | 1.6590 (estimate) |
| MDL | MFCD03547942 |
| Physical and Chemical Properties | Properties: white powder, with hygroscopic, tasteless or with a characteristic odor. |
| Use | For cosmetics, food processing and feed industry and other anti-corrosion |
Diazolidinyl urea - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 43 - May cause sensitization by skin contact |
| Safety Description | 36/37 - Wear suitable protective clothing and gloves. |
| WGK Germany | 2 |
| RTECS | YS2717000 |
| HS Code | 29339900 |
| Toxicity | LD50 orally in rats: 2.57 g/kg; dermally in rabbits: >2.0 g/kg (Berke, Rosen) |
Diazolidinyl urea - Reference Information
| LogP | 0.9 at 20℃ |
| EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
| antibacterial activity | diazoalkyl urea has broad-spectrum antibacterial activity and can inhibit Gram-negative and Gram-positive bacteria, it has a certain inhibitory effect on yeast and mold. |
| Application | diazoalkyl urea can be used for cream, liquid, shampoo, conditioner, liquid cosmetics and eye cosmetics and other residual and wash-off products, the product is approved by the United States and the European Union. The general addition amount is 0.1 ~ 0.3%, and it is better to add it at less than 50 ° C. It can be used with nipagin esters and IPBC to enhance its anti-corrosion effect. |
| Compatibility | compatibility with the various components present in cosmetics, the results showed that the antibacterial ability was not affected by the additives such as surfactants, proteins and Chinese herbal medicines in cosmetics. |
| biological activity | Diazolidinyl urea, a broad-spectrum preservative, is a formaldehyde-releasing compound that releases formaldehyde by decomposition. Diazolidinyl urea is effective against most contaminating microorganisms, especially Pseudomonas. |
| Use | used in cosmetics, food processing and feed industry as preservative |
Last Update：2024-04-09 20:52:54
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